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A hundred thousand, two hundred thousand tops

Dr. Deborah Birx once more laid out the benchmark this morning:

Joining TODAY from Washington, the response coordinator for the White House Coronavirus Task Force, Dr. Deborah Birx, says, “if we do things together well, almost perfectly, we could get in the range of 100,000 to 200,000 fatalities,” but adds, “we’re not sure all of America is responding in a uniform way.”

Note Guthrie’s reaction. Because it’s pretty clear that we are not doing things perfectly. And, by the way, it isn’t just because the city slickers are refusing to social distance. The rural red states are exploding too, mostly because the Trump voters there believe that it’s all a hoax.

1-2 hundred thousand are the numbers Trump has now named as the goal that will prove he did a really good job in containing the virus. I hate to be cynical but I can’t help but wonder if Birx and Fauci told him privately that it was actually unlikely in order to get him to keep the guidelines in place until the end of April, telling him that he’d look really, really good if “the numbers” come in lower.

I continue to be stunned at how much energy has to be expended to keep President Fauntleroy happy while the government is supposed to be all hands on deck to deal with this emergency.

For instance:

Politico reports:

The Food and Drug Administration on Sunday issued an emergency use authorization for hydroxychloroquine and chloroquine, decades-old malaria drugs championed by President Donald Trump for coronavirus treatment despite scant evidence.

The agency allowed for the drugs to be “donated to the Strategic National Stockpile to be distributed and prescribed by doctors to hospitalized teen and adult patients with COVID-19, as appropriate, when a clinical trial is not available or feasible,” HHS said in a statement, announcing that Sandoz donated 30 million doses of hydroxychloroquine to the stockpile and Bayer donated 1 million doses of chloroquine.

The move was supported by the White House, part of a larger Trump-backed effort to speed the use of anti-malaria drugs as a potential therapy for a virus that has no proven treatment or cure. FDA already has allowed New York state to test administering the medication to seriously ill patients, and some hospitals have added it to their treatment protocols.

“Let’s see how it works,” Trump said at a press briefing on Sunday, referencing New York state’s efforts. “It may. It may not.”

“Scientists in America and around the world have identified multiple potential therapeutics for COVID19, including chloroquine and hydroxychloroquine,” HHS Secretary Alex Azar tweeted on Sunday night, praising Trump and the EUA.

Lawmakers have ripped the administration’s bungled handling of the outbreak. But some now wonder if there’s more they could have done when it might have made a difference.Confirmed U.S. Cases: 156,931 | U.S. Deaths: 2,880Which workers are most at risk during the crisis?Coronavirus cases, tracked state by stateDo you work for a hospital? Tell us what you’re seeing

Career scientists have been skeptical of the effort, noting the lack of data on the drugs’ efficacy for coronavirus care and worried that it would siphon medication away from patients who need it for other conditions, calling instead for the agency to pursue its usual clinical trials. FDA’s move is expected to facilitate more access to the drugs by allowing more donations, and a second EUA is under consideration that would allow more manufacturers to produce it, said three officials.

Hydroxychloroquine, which is already available commercially in the United States, is commonly used to treat malaria, lupus and rheumatoid arthritis. The drug also has been touted as a therapy for coronavirus by an unusual assortment of investors, TV correspondents and even some advisers to the White House — including some advocates who overstated their claims and credentials — and been championed by guests on Fox News.

This has clearly been done for the sole purpose of shutting him the hell up. It certanly isn’t something the experts would normally approve:

“I would like to see who at FDA’s [Medical Countermeasures Initiative] signed off on this EUA despite the total lack of scientific evidence that chloroquine/hydroxychloroquine are beneficial in the treatment of COVID-19,” tweeted Luciana Borio, who served as FDA’s acting chief scientist between 2015 and 2017. “EUA is supposed to be issued when the evidence indicates that benefits outweigh the risks.”

I would have to assume that this is a whole different kind of risk-benefit analysis. I’m quite confident that they had to give him his magical snake oil cure as part of a bargain to keep him from listening to the greedheads telling him to order the country back to work. They didn’t want to do it but it probably seemed like the easiest way to appease him while causing the least amount of harm.

Trump has pushed to experiment with new therapies and not wait on the usual clinical protocols, given the unprecedented nature of the coronavirus pandemic. Asked by a POLITICO reporter whether his agencies should wait for more evidence on anti-malaria drugs, the president on Friday stressed the need for speed, alluding to disagreements with infectious-disease specialist Anthony Fauci — one of several officials who has privately counseled the president not to rush on unproven medicines.

“I think Tony would disagree with me … [but] we have a pandemic, we have people dying now,” Trump said, adding that he’d recently spoken with FDA and been frustrated by the agency’s pace.

“They indicated that we’ll start working on it right away. It could take a year,” the president said. “I said what do you mean a year? We have to have it tonight.”

He likes to say, “what do you have to lose?” Well:

However, a growing number of lupus and arthritis patients have complained that they’ve been unable to full their prescriptions amid ongoing shortages, and reports have emerged that some physicians are hoarding the drug for themselves.

I hope his “cure” turns out to be true. But every real expert I’ve heard on the subject doesn’t believe that the studies done so far merit this kind of trial. But you have to hope that Dr. Donald Trump is right on this and all the other experts are wrong even if it’s completely ridiculous. What else can we do?

Update: Twitter had Ingraham remove this for violating their terms of service:

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